Beliefs and beliefs about stem cells

Beliefs and beliefs about stem cells

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Can Stem Cells Grow? What can they be used for? These are a few requests that dispel the doubts.

In Hungary, there is no use of genealogists.

FALSE. In Hungary, since 2002, implantation of cord blood stem cells has been regularly performed, and the number of implantations has already exceeded one hundred.
The potential for medical application of the genitive cord is increasing. Numerous experts describe the current state as a period of exploration and healing in medicine. Nowadays, it is used in the treatment of multiple cord blood diseases, such as malignant tumors, bone marrow abnormalities, red blood cell diseases, and immune diseases. There are currently 5 Stem Cell Transplantation Centers in Hungary: St Laszlo Kourrzh, Budapest, University of Debrecen, University of Pecs, Borsod-Abaya-Zemplin County and University of Miskolc. Stem cell transplantation is a health care supported by OEP.

The amount of field cord removed is insufficient for an intervention.

FALSE. In the case of cord blood transplantation, it is not only the amount of blood taken at birth that is determined. Another important parameter is the white blood cell count per microliter. With these in mind, we can say that the value of the cord blood lineage lies in its ability to serve as a source of resources for the rehabilitation of the blood vessel system.
The final evaluation can be done after determining the number of stem cells in the blood.
With all of this in mind, we can say with certainty that the average amount taken is sufficient to repair the blood training system by about an hour. 40 kg in body. Patients with a higher body weight may be affected by this. sequential transplantation (implantation of other appropriate human cord units) so that the number of stem cells introduced into the body is appropriate for the body weight. There is also the possibility of implanting human cord blood stem cells with peripheral blood cells or stem cells derived from bone marrow.
In addition, the proliferation of stem cell proliferation technology is widespread worldwide, although this procedure is not yet feasible in Hungary.
In regenerative medicine (the new end of medicine that studies the transformation of mesenchymal stem cells into other stem cell lines), cell counts do not limit the therapeutic use of cells. There is a lot of research in this area and clinical studies based on them are underway.

Autologous genitalia is worse than allogeneic (whether related or not related).

FALSE. Today's medical science, along with conventional therapies, uses autologous hematopoietic stem cell therapy in combination with conventional therapies. The storage of neonatal stem cells means that we have a very fast access to content. Transplantation of specific hematopoietic stem cells can be used in the treatment of some cancers.
The advantage of using autologous stem cells is that there is no danger of GvHD, which is a complication after implanting an allogeneic (brotherly or non-sister) sample. This disease can be very harmful to the patient. Transplantation of autologous stem cells does not produce a cancer response called Graft versus Tumor or Graft versus Leukemia.
However, in cases where the disease is due to a defect in the stem cells (eg, severe aplastic anemia), such as adrenoleukodystrophy or severe immune deficiency syndrome (e.g., Wiskott's Aldrich syndrome) -Using the source is incorrect because it will not expel it. Autologous stem cell transplantation has many drawbacks, but it is absurd to say that your own genitalia is always worse than the other.
The fact is that out of the 8,000 transplants, only a few are using their own genetic engine, a couple of them know their brother, the rest are not related donors, only one person is like a statistic, just like one other person.

There is no proper technique for the proliferation of stem cells.

FALSE. The possibility of a glandular transplant is dependent on the number of white blood cells in a patient (minimum value 2 * 10).7/ kg body weight) and limited by the number of stem cells (minimum 2 * 105/ Testsъlykilogramm). Because of these limitations, researchers have begun to look for methods for reproductive stem cell proliferation. In the year 2000, in the United States, in vitro conditions were used to transplant human cord stem cells that had been multiplied in vitro by the AastromRepliCell method.
To date, many articles have been published on the potential of stem cell proliferation in a variety of specially prepared media (mediums, growth factors). According to various sources, more than a hundred in vitro implantation studies have been carried out on stem cells propagated in vitro. It is simply not true that there has been no progress in these studies in recent years.

Genital blood can only be used to cure leukemia.

FALSE. The success of transplantation of stem cells from the genitourinary system in Europe was based on the fact that it can be used to cure (and the number is increasing) cancerous diseases. Another major group of diseases that have been successfully treated with this method are non-neoplastic and neoplastic (solid tumors and leukemia) cancers.
There is a full list of 80 diseases for which this is already a common practice and for which clinical studies are in progress.
Few neoplastic disease can be cured without transplantation of stem cells. Some cancers (such as leukemias) are not used for the first appearance of stem cell intervention due to the low clinical incidence. Multiple occurrences of the disease warrant a transplant procedure, and the results are similar to those of standard chemotherapy but with a lower risk of developing complications.
In Poland, hematopoietic stem cells collected during therapy have been used in children for the treatment of the following diseases:
a, hypoplastic diseases (frequency of autologous transplantation): malignant lymphoma, acute myeloid leukemia, acute lymphoblastic leukemia, Hodgkin's disease, chronic myeloid leukemia, malignant hysticosis
b, solid tumors (according to the frequency of autologous transplants): neuroblastoma, Ewing's sarcoma, bone cancer, rhabdomyosarcoma, tumors of the central nervous system, and even a small number of tumors in children.

The whole family can use the braiding cord.

FALSE. The stored genetic cord can only be used for treatment (without further testing of the antigen) from which it was removed. The results of the compatibility tests are considered to be useful in the patient's sibling.
Lesser HLA antigens need to be matched in a human cord blood sample than when using bone marrow or peripheral blood stem cells.

The infected genius cannot be used.

FALSE. The decision on the possible use of an infected sample (which appears in 5-7% of the total) is solely and exclusively in the hands of the transplantation institute. The use of a specimen depends on the microbial contamination of the blood and the conditions of transplantation (single or sequential intervention where only a part is infected). There are many cases in the literature where an infected genetic cord has been used. The position complies with European legislation (Council Directive 2006/17 / WE of the European Council) and the AABB (American Associaton of Blood Bank).

Family Family Banks are illegal in Hungary.

FALSE. No. 60/2003. (X. 20.) EszCsM. The Decree-Law of 2000 has established the legal framework necessary for the operation of the health services of stem cells.

Family Family Genealogy Banks are exclusively for children.

FALSE. The learner is owned by the child's parents or guardian and is owned by the child himself / herself. It is possible to transfer the sibling stored in the bank to the sibling at the discretion of the eligible owner or adult owner. After further specimen and antigenic matching between the recipient and the patient, the blood is expected to be usable from the patient's sibling. The cord blood can be delegated to any baby who needs this type of transplant (matching, with the right number of cells). Family Genetic Banks will be able to ship the sample under appropriate conditions to any authorized transplant provider.

Transgenic stem cells can only differentiate into hematopoietic stem cells.

FALSE. The umbilical cord contains single cells that differentiate into bone marrow cell precursors, which then become red blood cells, white blood cells, and platelets. Currently, the most common use of hematopoietic stem cells is in the transplantation of cancerous and non-cancerous (acquired and acquired) diseases.
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The amount of field cord taken depends on the collector.

FALSE. The features of the aforementioned device do not affect the amount of blood drawn, although there may be a problem if the letter needle is too small. You should always be very careful about the safety of the mother and baby when collecting the cord. Professional mail is needed to get the right amount. The number of stem cells depends on the amount of blood removed, the unique anatomical features of which the length of the cord appears to be most important. The amount of blood taken depends on the method of delivery, the size of the placenta, and the skill of the physician.